The increased throughput of the PacBio® Sequel® System enables multiple microbes to be sequenced on a single
“A comprehensive view of the bacterial genome, including genes, regulatory regions, IS elements, phage integration sites, and base modifications is vital to understanding key traits such as antibiotic resistance, virulence, and metabolism. Single Molecule, Real-Time Sequencing technology provides complete genomes, often assembled into a single contig,” said
Key benefits of the streamlined workflow — from library preparation to genome assembly — include cost reduction through multiplexing, faster time to results, and advanced genome assembly parameters optimized for microbial genomes.
PacBio’s participation in a historic project to sequence 3,000 important strains of bacteria housed at the UK’s National Collection of Type Cultures (NCTC) will also be highlighted. In partnership with the
Scientific Program Highlights
Scientific advances enabled by PacBio long-read sequencing technology will be showcased in more than 25 posters and presentations spanning basic molecular biology and physiology, antimicrobial agents and resistance, environmental science, ecology and evolution, and clinical and public health microbiology.
- An update on the recently completed NCTC 3000 collaboration, “NCTC 3000: The World’s Largest Collection of Bacterial Reference Genomes”, presented by
Sarah Alexanderof Public Health England, on Friday, June 8, at 11 a.m.
- A poster, “Acinetobacter baumannii as a Pathogen of War: New Insights from Whole Genome Sequencing”, presented by
Erik Snesrudof the Walter Reed Army Institute of Research(WRAIR), on Saturday, June 9, at 11 a.m.
- A session on Evolutionary Histories of Microbial Genomes, featuring the talk “Chromosome Rearrangement, Gene Amplification, and Insertion Sequence Elements in the Genome Evolution of Bordetella pertussis and the Genus Bordetella” by
Michael Weigandof the CDC, on Saturday, June 9at 11 a.m.
- A rapid-fire presentation, “Microbe, Know Thy Host,” featuring a presentation about an award-winning abstract, “Clonal Evolution and Genomic Diversification of Bordetella hinzii in an Immunocompromised Host,” by
Adrien Launayof the NIH, on Saturday, June 9, at 1:45 p.m.
PacBio Principal Scientist
ASM meeting attendees and other interested scientists can apply for free SMRT Sequencing and bioinformatics analysis through the annual Microbial Genomics SMRT Grant Program, sponsored in partnership with the University of Maryland’s
More information is available at https://www.pacb.com/smrt-science/smrt-grant
About Pacific Biosciences
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Source: Pacific Biosciences, Inc.